Ginseng Extract

For thousands of years, Panax ginseng (commonly known as ginseng) has been valued in traditional Eastern-Asian medicine as a tonic for vitality, resilience and overall wellness. In recent decades it has been adopted in Western nutraceuticals and cosmeceuticals for its adaptogenic properties - supporting the body's capacity to respond to physical, metabolic and environmental stressors.^{REF 1, REF 2} 

The key bioactive compounds in ginseng - ginsenosides - include both protopanaxadiol (PPD) types (such as Rb1, Rb2, Rc, Rd) and protopanaxatriol (PPT) types (such as Rg1, Re). These specific ginsenosides have been investigated for their roles in hair biology^{REF 3,  REF 4}  as well as broader wellness endpoints.^{REF 5, REF 6} 

In the realm of hair-care and scalp-focused cosmeceuticals, ginseng extract has become a premium botanical active, appearing in high-end shampoos, serums and scalp treatments worldwide. Mechanistic investigations show it may support micro-circulation, mitigate oxidant stress, regulate apoptosis (programmed cell death) in follicular cells and potentially inhibit 5α-reductase-linked pathways of hair-loss.^{REF 7}  Together, these data reinforce the role of ginseng as a scientifically credible ingredient for scalp vitality, hair-density support and follicle-health formulations.^{REF 8,  REF 9} 

Regulatory assessments and clinical trials support a favourable safety profile for standardised ginseng extracts. Systematic reviews of randomised controlled trials show minimal adverse effects under appropriate dosing, though as with all actives, formulation context and individual factors should be considered.^{REF 10}

In a multicenter, double-blind, randomised, placebo-controlled trial to assess the safety and tolerability of Korean Red Ginseng in healthy adults, daily doses of 3 g of extract (equivalent to ~20 mg of ginsenosides per day) over 24 weeks was considered both safe and generally well tolerated in healthy adults.^{REF 11} Health Canada concludes that Panax ginseng root extract can be used safely in supplemented foods only when total ginsenoside intake does not exceed 8 mg/day.^{REF 12} The National Centre for Complementary and Integrative Health (NCCIH) states that short-term (up to 6 months) oral use of ginseng in recommended amounts appears safe for most people. ^{REF 13} 

Ginseng is not recommended for infants or young children, and individuals who are pregnant, breastfeeding, diabetic, or taking medications that affect blood pressure, glucose, or coagulation should seek medical advice before use. Long-term continuous intake beyond six months has not been adequately studied and should be avoided unless supervised by a healthcare professional.