Copper Peptides

What are Copper Peptides?

Copper peptides, particularly GHK-Cu (glycyl-L-histidyl-L-lysine copper), are widely used in advanced cosmetic and dermatological formulations for their powerful anti-aging, skin regeneration, and hair growth benefits. GHK is a naturally occurring tripeptide present in human plasma, saliva and urine, with a strong affinity for copper ions, forming the biologically active complex GHK-Cu.^{REF 1} 

Originally discovered in the 1970s, GHK-Cu has been extensively studied for its ability to support wound healing, collagen synthesis, and tissue repair. Its ability to rejuvenate skin by reducing wrinkles, improving elasticity, and combating photoaging has led to its inclusion in many premium anti-aging skincare products.^{REF 2}

In addition to its skin benefits, GHK-Cu is increasingly recognised in the field of hair restoration. Research indicates that it stimulates hair follicle health, prolongs the anagen (growth) phase, and supports the repair of scalp tissue - making it a promising adjunct to hair loss treatments, including topical minoxidil formulations.^{REF 3}

The effectiveness of copper peptides is believed to arise from their ability to deliver bioavailable copper - an essential cofactor in numerous enzymatic and cellular functions - without inducing toxicity.^{REF 4}

Recent gene expression studies also suggest that GHK-Cu helps modulate key pathways involved in oxidative stress, inflammation, and skin remodelling, reinforcing its reputation as a multifunctional active ingredient in both cosmeceuticals and hair regrowth serums.^{REF 5} 

Key benefits:

• Supports collagen production and skin elasticity
• Reduces wrinkles, fine lines, and signs of photoaging
• Stimulates hair growth and strengthens follicles
• Enhances wound healing and tissue regeneration
• Provides anti-inflammatory and antioxidant activity
• Ideal for integration into custom skincare and hair loss formulations

Common applications:

• Anti-aging facial creams and serums
• Scalp serums and hair regrowth boosters
• Post-procedure recovery products
• Microneedling or derma-roller protocols